Prevent cervical cancer

All this when we hear the word cancer, then we immediately appalled. Some people even tried to avoid discussion / discussion about this disease with fear. However, like do not like the occurrence of this cancer is increasing just as the shifting of human lifestyle, including eating patterns, patterns of sexual relationships, and the rise of food additives, beverages and cosmetics that would trigger the cancer.

Therefore, unfortunately, if that fear makes us not want to know that eventually led to antipathy toward the disease is obviously a vicious killer (appropriate name). Whereas some cancers, can actually be prevented by various means including certain anticancer vaccination.

What is cancer?
Cancer is the growth of the cells in the body (especially starting at the particular organ vulnerable reply) is abnormal. Abnormality of cancer, among others reflected in the ability of cells to grow unlimited. In normal cells, there is a mechanism if the cells are large and have reached a certain amount, then there will be a signal that inhibits further cell growth and more. In addition to the normal cells have the ability to recognize the contact with other cells (cell surface contact), so that the cells will stop the self, not divide intensively because of surface tension / surface contact with other cells. But in cancer cells, the ability to split the very large cells (ploriferasi = multiply).

How does cancer occur?

The process begins with the early stages of the entry preinisiasi trigger (could be free radicals from anywhere = food, beverages, cosmetics, additives, environmental). The materials that trigger cancer called carcinogenic compounds. An example is in Table 1.

Table 1. Carcinogenic substances that may enter the body
Possible Source of carcinogenic substances cancers
Ultraviolet A, B rays of the sun Melanoma / skin cancer
Nitrosamines additive sodium nitrite in sausage and corned beef (red color of meat), kebabs / BBQ Cancer (general)
Benzo (a) piren Cigarettes Lung Cancer
Rhodamin B dyes paper but added to foods, beverages, cosmetics (red) skin cancer, cancer (general)
Human papilloma virus (HPV), especially sexual Environment cervical cancer

The entry of carcinogenic substances will trigger genetic mutations in DNA. There was a process of initiation. This process will continue to happen as the growth and cell division, then comes the stage of proliferation. With so many abnormal cells, it takes a lot nutrisis and oxygen, then the cancer cells have the ability to form new blood vessels (angiogenesis). Angiogenesis in addition to functioning as the main material supply for cell growth, but also serves as the spread of cancer cells in other organs because of cancer cells can spread to accompany the flow of blood (angiogenesis) and lymph vessels (limfogenesis). The second is called metastase distribution.

At the initiation stage of pre and biases so abnormal cells do not grow as malignant, only as a tumor (benign). But when you grow indefinitely and there is malignancy, so-called cell cancer (malign). Similarly, the immune power, may well be able to inhibit the growth of abnormal cells, so that does not appear either as a tumor especially cancer.

Ca cervix?

Cancer that occurs in cells in the cervical canal, known as cervical cancer. Although the world of this cancer's ability as an assassin has not surpassed lung cancer, but remained the world's attention because the incidence is increasing sharply. In one state in Australia, there are at least 85 reported cervical cancer each year, and 40 patients died. Unfortunately, data on
Indonesia is not yet available, but perhaps it was not a little number. Cervical cancer caused by HPV, a virus that has a double stranded DNA is small but has a protein capsid. Last reported capsid most important is the type of L1.

The main source of infection (75%) is a sexual relationship. HPV attacks began a sexual maturity, starting 9-year-olds to senior citizens aged 70 years. Means that there was sexual contact, it is possible for a woman's life was under threat of HPV.

Symptoms

In some patients, symptoms did not appear significant (asimtomatis). However, some symptoms of HPV infection leads to the develop into cervical cancer among othe aware of:

* The emergence of pain after having sex
* Post-coitus bleeding
* The emergence of more mucus and smelly in the birth canal
* Incidence of bleeding after intercourse in couples who had been menopausal

Therefore recognizable symptoms of post-sexual relationship, then disaranka to couples who had been menopausal for permanent sexual intercourse. It could be the emergence of cancer has long before reaching menopause, then an elderly couple masik active sexually, will facilitate this type of cancer detection.

HPV types 6 attack in particular, 11, 16 and 18.

Early detection.

Until now, early detection of cancer will greatly help the success of cancer therapy. Included in this cervical cancer. One of the early detection methods that have been used for more than 60 years is a Pap smear test. Detection method by taking this cervical apus was first introduced by Dr. George Papanicolou in the year 1943, therefore, called a Pap test as an abbreviation of the name of this inventor. This method is quite sensitive and specific compared with other methods such as fluorescent, IR and cervicograph.

Pap tests should be performed once every 2 years, except in special cases should be done more frequently (eg, IUD users). Since a woman has been sexually active, it must immediately do this test. The doctor will take on the cervical cells using Speculum to open the cervix, and a spatula to take lear servi. Tues then placed in a glass object, to be examined by microscopy. Some possibilities in the Pap test: unsatisfactory (it must be repeated after 6 weeks), found an infection / inflammation, or the existence of atypia. So better to obtain a satisfactory examination results, should be done around 1-2 weeks after completion of menstruation. At the time of taking specimens, there is little discomfort and pain. But this should not make fear for women, because considering the usefulness of this test for our survival. More comfortable when done by physicians and women who obsgyn tips have known better.

Prevention

Not at all types of cancer preventive measures can be meaningful. But in this cervical cancer, a vaccination will be able to reduce the risk of this cancer 50%. Since 1991 research has been done about 20 types of vaccine for cervical cancer is. One that has begun to pass clinical trials / clinical trials is Gardasil. In some European countries the vaccine is made by several different manufacturers including Glaxo. However, condom use should be campaigned as a preventive one, too., But certainly not anjura for change of partners in sexual relationships.

Is Gardasil?

Gardasil is the name of the patent medicine made from a virus like particles (VLPs) of HPV capsid L1, which has been purified by qualified. This protein is made by fermentation by recombinant technology using the yeast Saccharomyces cerevisae. These drugs form a suspension containing 0.5 ml of 6 type 20ug, 40ug types 11 and 16, 20 ug type 18. This vaccine was believed able to lose more than 75% cases of cervical cancer are thought to involve humoral immune response as a mechanism of action.

In Australia, began in 2007 will be required Gardasil vaccination for girls aged 9 years to 26 years as an effort to suppress the incidence through preventive action. So the vaccine is not as therapy, and in women aged more than 26 years is not effective. Vaccination performed 2 times, ie, 1 month and 5 months after the first act of vaccinations given. The plan of this vaccine free to girls 9 years old to 26 years throughout Australia.

TIP

Therefore, if the family is still there 9-26 year old girl should ikutkanlah Gardasil vaccination program. And for women who have been sexually active / married, immediately and rutinlah do pap smear test, followed by action to reduce consumption or contact with carcinogenic materials.